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wegeners granulomatosis

Wegener's Granulomatosis

  • Wegener's granulomatosis is an uncommon disease that involves inflammation of blood vessels (vasculitis).
  • Symptoms of Wegener's granulomatosis include fatigue, weight loss, fevers, shortness of breath, bloody sputum, joint pains, and sinus inflammation.
  • Diagnosis of Wegener's granulomatosis is confirmed by detecting both abnormal cellular formations, called granulomas, and vasculitis.
  • Treatment is directed toward stopping the inflammation process by suppressing the immune system.

References:

Clinical Primer of Rheumatology, Lippincott Williams & Wilkens, edited by William Koopman, et al., 2003.

Kelley's Textbook of Rheumatology, W B Saunders Co, edited by Shaun Ruddy, et al., 2000.

American College of Rheumatology National Meeting, November 2005, 2006, 2007.